New Proof that Chemotherapy Promotes Cancer
December 3rd, 2008 Posted in prostate chemotherapyThe same chemotherapy that cures a patient’s prostate cancer may increase that patient’s chances of developing cancer later in life in tissue adjacent to the original cancer, new research by the Buck Institute for Age Research indicates.
Cells shut down and stop dividing when their DNA is damaged, as occurs during chemotherapy. But the Novato institute’s new study found that when the cells shut down they spew proteins into their surrounding environment. The process, called cellular senescence, causes inflammation and sets up conditions that support the development of age-related diseases including, ironically, cancer.
The study has major implications for age research because it suggests that a cellular response that likely evolved to protect from cancer early in life can promote disease later in life,