Scientists Develop New Prostate Cancer Cell Line
October 18th, 2008 Posted in prostate cancerResearchers at the Kimmel Cancer Center at Jefferson have established a laboratory prostate cancer cell line they believe will become a valuable research tool in both understanding and treating prostate cancer.
The new prostate cancer cell line reflects how the cancer can initially be fueled by the male hormone androgen and how the cells can then morph into hormone-resistant, aggressive tumors. The majority of existing prostate cancer cell lines does one or the other, but not both.
This cell line provides a new experimental model for studies on androgen-related growth of prostate cancer cells and for research on genetic changes and molecular pathways involved in growth of androgen-deprived prostate cancer cells.