New report shows most men with low PSA undergo aggressive therapy
July 27th, 2010 Posted in prostate cancerAccording to a report in the July 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals, most men who are diagnosed with prostate cancer appear to under undergo aggressive therapy, even if they have a low prostate-specific antigen (PSA) level and low-risk disease.
Researchers at the Cancer Institute of New Jersey, New Brunswick, concluded results underscore the fact that PSA level, the current biomarker, is not a sufficient basis for treatment decisions. They suggest that without the ability to distinguish indolent from aggressive cancers, lowering the biopsy threshold might increase the risk of overdiagnosis and overtreatment.