Histological prostatitis and its correlation with PSA density
December 19th, 2009 Posted in prostate cancerA new study at Sao Paolo University, Brasil, aimed to determine the incidence of asymptomatic, histologically proven prostatitis in men with symptoms of benign prostate hyperplasia and to observe the correlation between asymptomatic prostatitis and prostate specific antigen (PSA) density.
histological prostatitis and group II included patients with the absence of histological prostatitis. The mean PSA densities were compared.
Histological evidence of prostatitis was observed in 145 patients. In this group, the mean PSA density was 0.136 +/- 0.095. In 38 cases, there was no evidence of inflammation upon histological examination of the surgical samples. In these 38 cases, the mean PSA density was 0.126 +/- 0.129. No statistically significant differences were detected between the two groups; the p-value is 0.124.
Abnormal PSA density should not be attributed to the inflammatory prostatitis process.