prostate-report.org

A promising target for prostate cancer therapies

In an article that is being published today as an advanced online publication by the journal Nature, scientists at Dana-Farber Cancer Institute report they have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they describe as a “powerhouse” that drives runaway cell growth.

The researchers say the growth-stimulating molecule called p110beta — part of a cellular signaling network disrupted in several common cancers — is a promising target for novel cancer therapies designed to shut it down.