Diabetes and outcomes after radical prostatectomy
January 26th, 2010 Posted in prostate cancer risksDiabetes is associated with lower prostate cancer risk. The association of diabetes with prostate cancer outcomes is less clear. A new stydy at Duke University School of Medicine, Durham, USA, examined the association between diabetes and outcomes after radical prostatectomy and tested whether associations varied by race and/or obesity.
In a radical prostatectomy cohort, diabetes was not associated with BCR. In the secondary analysis, diabetes was associated with more aggressive disease in obese white men and less aggressive disease for all other subsets. If externally validated, these findings suggest that among men with prostate cancer, the association between diabetes and prostate cancer aggressiveness may vary by race and obesity.