Better detection of aggressive prostate cancer
September 27th, 2009 Posted in prostate cancer diagnosisA study published in the British Journal of Cancer reveals Cancer Research UK scientists have discovered a molecular ‘flag’ that predicts survival from prostate cancer at diagnosis.
The research team based at the University of Liverpool measured the levels of a protein called heat shock protein-27 (Hsp-27) in prostate tissue samples taken from 553 men at the time they were diagnosed with prostate cancer. During a 15-year follow-up, the research showed that those men who tested positive for Hsp-27 at diagnosis were almost twice as likely to die from prostate cancer, than men who did not have the protein.
These findings suggest that Hsp-27 could be used as a potential test to distinguish men with the aggressive forms of the cancer that need immediate treatment from men with slow-growing forms of prostate cancer, and with which they can live with for many years. At the moment, there are no reliable tests to make this distinction.